Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis Pdf

Book Detail
Edition:
Release: 1998-12
Publisher: World Health Organization
Binding: Paperback
ISBN/ASIN: 9241545224
Format: hardcover, kindle, PDF, EPUB

Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis pdf
Description

This book provides comprehensive guidelines for the design, implementation, and interpretation of preclinical studies and clinical trials of agents undergoing investigation for the management of osteoporosis. Noting the magnitude of the public health problem caused by osteoporosis and related fractures, the book responds to the urgent need for a cohesive and rational approach to the search for new therapeutic or preventive agents. Recommended principles and methods reflect the consensus reached by a large number of international experts, representatives of the pharmaceutical industry, and drug regulatory authorities.

The book opens with a brief discussion of the current and future public health problem caused by osteoporotic fractures, followed by conceptual and operational definitions of osteoporosis and a recommended classification of four intervention categories that facilitate the definition of treatment objectives and the design of targetted studies.
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