Book Detail
Edition: 1
Release: 1996-12
Publisher: World Health Organization
Binding: Paperback
ISBN/ASIN: 9283212665
Format: hardcover, kindle, PDF, EPUB
Some Pharmaceutical Drugs (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans) pdf
Description
Evaluates the carcinogenic risk to humans posed by the therapeutic use of thirteen pharmaceutical drugs, including eight benzodiazepines and related compounds used for the treatment of anxiety and as sedatives and anticonvulsants, three triphenylethylene anti-oestrogenic compounds developed for the treatment of breast cancer, and two cholesterol-lowering agents used to treat patients at high risk for cardiovascular disease. Evaluations are based on a critical assessment of all data available for these compounds, including abundant information on pharmacokinetic and pharmacodynamic effects, precise studies of exposure-response relationships, and findings that shed light on mechanisms of carcinogenic action.
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